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NativeExtract™ Human GRM5 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX188)

Datasheet
This product is recombinant Human GRM5 protein in native nanodisc form. The synthetic compound we developed can solubilize the GRM5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GRM5
  • Protein Length
  • Full length
  • Molecular Weight
  • 132.5kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GRM5
  • Full Name
  • Glutamate metabotropic receptor 5
  • Introduction
  • This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • mGlu5; GPRC1E; MGLUR5; PPP1R86; glutamate receptor, metabotropic 5; protein phosphatase 1, regulatory subunit 86; GRM5; Glutamate metabotropic receptor 5

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