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NativeExtract™ Human HTR1A Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX352)

Datasheet
This product is recombinant Human HTR1A protein in native nanodisc form. The synthetic compound we developed can solubilize the HTR1A protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR1A
  • Protein Length
  • Full length
  • Molecular Weight
  • 46.1kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HTR1A
  • Full Name
  • 5-hydroxytryptamine receptor 1A
  • Introduction
  • This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.
  • Alternative Names
  • G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1; 5-HT1a receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; guanine nucleotide-binding regulatory protein-coupled receptor; HTR1A; 5-hydroxytryptamine receptor 1A

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