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NativeExtract™ Human HTR1B Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX351)

Datasheet
This product is recombinant Human HTR1B protein in native nanodisc form. The synthetic compound we developed can solubilize the HTR1B protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR1B
  • Protein Length
  • Full length
  • Molecular Weight
  • 43.6kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HTR1B
  • Full Name
  • 5-hydroxytryptamine receptor 1B
  • Introduction
  • The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.
  • Alternative Names
  • S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT-1B; 5-HT1DB; 5-HT-1D-beta; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; serotonin 1D beta receptor; serotonin receptor 1B; HTR1B; 5-hydroxytryptamine receptor 1B

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