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NativeExtract™ Human MC2R Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX331)

This product is recombinant Human MC2R protein in native nanodisc form. The synthetic compound we developed can solubilize the MC2R protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MC2R
  • Protein Length
  • Full length
  • Molecular Weight
  • 33.9kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • MC2R
  • Full Name
  • Melanocortin 2 receptor
  • Introduction
  • MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.
  • Alternative Names
  • ACTHR; adrenocorticotropic hormone receptor; ACTH receptor; MC2 receptor; adrenocorticotropin receptor; corticotropin receptor; melanocortin 2 receptor (adrenocorticotropic hormone); MC2R; Melanocortin 2 receptor

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