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NativeExtract™ Human NPSR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX144)

Datasheet
This product is recombinant Human NPSR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the NPSR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NPSR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.7kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • NPSR1
  • Full Name
  • Neuropeptide S receptor 1
  • Introduction
  • This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • GPRA; NPSR; VRR1; ASRT2; PGR14; GPR154; neuropeptide S receptor; G-protein coupled receptor 154; G-protein coupled receptor PGR14; G-protein coupled receptor for asthma susceptibility; vasopressin receptor-related receptor 1; NPSR1; Neuropeptide S receptor 1

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