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NativeExtract™ Human P2RY1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX83)

Datasheet
This product is recombinant Human P2RY1 protein in native nanodisc form. The synthetic compound we developed can solubilize the P2RY1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RY1
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.1kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • P2RY1
  • Full Name
  • Purinergic receptor P2Y1
  • Introduction
  • The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
  • Alternative Names
  • P2Y1; SARCC; ADP receptor; ATP receptor; P2 purinoceptor subtype Y1; platelet ADP receptor; purinergic receptor P2Y, G-protein coupled, 1; suppressing androgen receptor in renal cell carcinoma; P2RY1; Purinergic receptor P2Y1

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