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NativeExtract™ Human P2RY11 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX77)

Datasheet
This product is recombinant Human P2RY11 protein in native nanodisc form. The synthetic compound we developed can solubilize the P2RY11 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RY11
  • Protein Length
  • Full length
  • Molecular Weight
  • 40.3kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • P2RY11
  • Full Name
  • Purinergic receptor P2Y11
  • Introduction
  • The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.
  • Alternative Names
  • P2Y11; P2Y purinoceptor 11; purinergic receptor P2Y, G-protein coupled, 11; P2RY11; Purinergic receptor P2Y11

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