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NativeExtract™ Human PTGDR2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX371)

Datasheet
This product is recombinant Human PTGDR2 protein in native nanodisc form. The synthetic compound we developed can solubilize the PTGDR2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTGDR2
  • Protein Length
  • Full length
  • Molecular Weight
  • 43.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • PTGDR2
  • Full Name
  • Prostaglandin D2 receptor 2
  • Introduction
  • This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
  • Alternative Names
  • DP2; DL1R; CD294; CRTH2; GPR44; G-protein coupled receptor 44; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; chemoattractant receptor-homologous molecule expressed on TH2 cells; putative G-protein coupled receptor 44; PTGDR2; Prostaglandin D2 receptor 2

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