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NativeExtract™ Human PTGER1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX69)

Datasheet
This product is recombinant Human PTGER1 protein in native nanodisc form. The synthetic compound we developed can solubilize the PTGER1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTGER1
  • Protein Length
  • Full length
  • Molecular Weight
  • 41.8kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • PTGER1
  • Full Name
  • Prostaglandin E receptor 1
  • Introduction
  • The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
  • Alternative Names
  • EP1; prostaglandin E2 receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1 (subtype EP1), 42kD; prostaglandin E receptor 1 (subtype EP1), 42kDa; prostaglandin E receptor 1, subtype EP1; prostanoid EP1 receptor; PTGER1; Prostaglandin E receptor 1

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