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NativeExtract™ Human SSTR5 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX43)

Datasheet
This product is recombinant Human SSTR5 protein in native nanodisc form. The synthetic compound we developed can solubilize the SSTR5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SSTR5
  • Protein Length
  • Full length
  • Molecular Weight
  • 39.2kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • SSTR5
  • Full Name
  • Somatostatin receptor 5
  • Introduction
  • Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
  • Alternative Names
  • SS-5-R; somatostatin receptor type 5; somatostatin receptor subtype 5; SSTR5; Somatostatin receptor 5

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