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NativeExtract™ Human TLR9 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX454)

Datasheet
This product is recombinant Human TLR9 protein in native nanodisc form. The synthetic compound we developed can solubilize the TLR9 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TLR9
  • Protein Length
  • Full length
  • Molecular Weight
  • 115.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TLR9
  • Full Name
  • Toll like receptor 9
  • Introduction
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
  • Alternative Names
  • TLR9; CD289; toll-like receptor 9; UNQ5798/PRO19605; Toll like receptor 9

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