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Yellow fever virus Envelope virus-like particles (YFV Envelope VLPs) (CAT#: S01YF-0922-KX1553)

Datasheet
Recombinant Yellow fever virus Virus-like Particle (YFV VLPs) are produced in mammalian HEK293 cells, assembled with Envelope protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. YFV VLPs can be used in the development of YFV diagnostics and in vaccine development and R&D (including use as an immunogen).

Product Specifications

  • Structural Proteins
  • Envelope protein
  • Expression Systems
  • HEK293 expression system
  • Form
  • Liquid
  • Alternative Names
  • Yellow fever virus virus-like particles; YFV VLPs; Yellow fever virus; YFV virus-like particles; VLPs; Virus-like Particles
  • Storage
  • Store at -80 °C long term. Avoid repeated freeze/thaw cycles.
  • Sequence
  • ahcigitdrdfiegvhggtwvsatleqgkcvtvmapdkpsldislqtvaidgpaearkvcysavlthvkindkcpstgeahlaeendgdnackrtysdrgwgngcglfgkgsivacakftcaksmslfevdrtkiqyviraqlhvgakqenwntdiktlkfdalsgsqeaeftgygkatlecqvqtavdfgnsyiaemekdswivdrqwaqdltlpwqsgsggtwremhhlvefepphaatirvlalgnqegslktaltgamrvtkdendnnlyklhgghvscrvklsaltlkgtsykmctdkmsfvknptdtghgtvvmqvkvpkgapckipvivaddltaavnkgilvtvnpiastnddevlievnppfgdsyiivgtgdsrltyqwhkegssigklftqtmkgaerlavmgdaawdfssaggfftsvgkgihtvfgsafqglfgglswitkvimgavliwvgintrnmtmsmsmilvgvimmflslgvga-HHHHHH

Virus Background

  • Virus Family
  • Flaviviridae
  • Virus Species
  • Yellow fever virus
  • Virus Overview
  • Yellow fever is caused by yellow fever virus, an enveloped RNA virus 40-50 nm in width, the type species and namesake of the family Flaviviridae. The positive-sense, single-stranded RNA is around 10,862 nucleotides long and has a single open reading frame encoding a polyprotein.Host proteases cut this polyprotein into three structural (C, prM, E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5); the enumeration corresponds to the arrangement of the protein coding genes in the genome.
  • Virus Structure
  • Enveloped, positive-sense, single-stranded RNA virus
  • Related Disease
  • Fever, chills, loss of appetite

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