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Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv4-Ig)  (CAT#: FVTIG-012)

Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-AR scFv is fused to the CH1 domain of a heavy chain and another anti-DNA scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can enter prostate cancer cells and inhibits androgen receptor function. It is designed for the research of prostate cancer therapy.
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Specifications

Targets
AR & DNA
Type
Appended IgGs
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Prostate cancer

Targets

Target 1
AR
Gene ID
UniProt ID
Alternative Names
AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4
Target 2
DNA
Alternative Names
DNA; Deoxyribonucleic acid
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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