Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) (BSTF-001)

Recombinant Anti-B cell lymphoma BCL1 Idiotype x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-B cell lymphoma BCL1 Idiotype scFv is fused to the N-terminus of Fc via a hinge region while another anti-CD64 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget immune cells to tumor cells. It is designed for the research of B cell lymphoma therapy.

Datasheet INQUIRY

Specifications

Targets

B Cell Lymphoma BCL1 Idiotype & CD64

Type

scFv-Fc-scFv

Species Reactivity

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma

Targets

Target 1

B Cell Lymphoma BCL1 Idiotype

Alternative Names

B cell lymphoma BCL1 Idiotype; B cell lymphoma; BCL1; Idiotype; Id; 31D1; 32D1

Target 2

CD64

Gene ID

14129

UniProt ID

P26151

Alternative Names

FcγRI; FCGR1A; Fc fragment of IgG, high affinity Ia, receptor (CD64); CD64; FCRI; CD64A; IGFR1; high affinity immunoglobulin gamma Fc receptor I; fcgammaRIa; Fc-gamma RI; fc-gamma RIA; Fc gamma receptor; IgG Fc receptor I; Fc-gamma receptor I A1; Fc fragment of IgG, high affinity Ia, receptor for (CD64); FCGR1B, FCGR1C

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-001)

Specifications

Targets

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