Home > Products > CD133 & EGFR > Recombinant Human Anti-CD133 x Human Anti-EGFR Bispecific Antibody (Fab-Fv)

Recombinant Human Anti-CD133 x Human Anti-EGFR Bispecific Antibody (Fab-Fv)  (CAT#: FABFV-H208)

Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-CD133 antibody are fused with the VL and VH domains of an anti-EGFR antibody respectively. It can form natural in vivo heterodimerization. This BsAb can target brain tumor stem cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors therapy.
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Specifications

Targets
CD133 & EGFR
Type
Fab-Fv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors

Targets

Target 1
CD133
Gene ID
8842
UniProt ID
O43490
Alternative Names
PROM1; prominin 1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; prominin-1; hProminin; antigen AC133; prominin-like protein 1; hematopoietic stem cell antigen
Target 2
EGFR
Gene ID
1956
UniProt ID
P00533
Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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