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Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (IgG-scFv)  (CAT#: IGFV-071)

Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (IgG-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget T cells to HIV infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.
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Specifications

Targets
CD3 & CD8
Type
IgG-scFv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD8
Gene ID
UniProt ID
Alternative Names
CD8A; CD8a molecule; Cluster of differentiation 8; CD8; MAL; p32; Leu2
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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