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Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-158)
Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-EGFR scFv is fused to the N-terminus of Fc via a hinge region while another anti-ZnO scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can be used in immunoassay of Head and neck cancer; Non-small cell lung cancer (NSCLC); Gastric cancer; Lung cancer; Colorectal cancer (CRC); Solid tumors.
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