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CD28 & CD40 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Diabody) Human CD28 CD40 Inquiry
T-BSDB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Diabody) Human CD28 CD40 Inquiry
SCIGG-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scIgG) Human Single chain IgGs CD28 CD40 Inquiry
SCIGG-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scIgG) Human Single chain IgGs CD28 CD40 Inquiry
FVTIG-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD28 CD40 Inquiry
FVTIG-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD28 CD40 Inquiry
BSSG-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD28 CD40 Inquiry
BSSG-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD28 CD40 Inquiry
IGLFV-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD28 CD40 Inquiry
IGLFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD28 CD40 Inquiry
BSGV-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD28 CD40 Inquiry
BSGV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD28 CD40 Inquiry
BSDG-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD28 CD40 Inquiry
BSDG-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD28 CD40 Inquiry
BABFV-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD28 CD40 Inquiry
BABFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD28 CD40 Inquiry
FABVC-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD28 CD40 Inquiry
FABVC-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD28 CD40 Inquiry
SCDBC-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
SCDBC-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
BSDBC-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
BSDBC-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
SCDBF-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
SCDBF-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
BSFVF-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
BSFVF-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
BSDBF-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
BSDBF-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD28 CD40 Inquiry
BSTF-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BSTF-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BSCFV-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BSCFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
MNAB-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
MNAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BSFC-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BSFC-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BSCC-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BSCC-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD28 CD40 Inquiry
BIBD-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Bibody) Human Bibody CD28 CD40 Inquiry
BIBD-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Bibody) Human Bibody CD28 CD40 Inquiry
FABFV-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 CD40 Inquiry
FABFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 CD40 Inquiry
MiniB-H232 Recombinant Human Anti-CD28 x Human Anti-CD40 Bispecific Antibody (Minibody) Human Minibody CD28 CD40 Inquiry
MiniB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Minibody) Human Minibody CD28 CD40 Inquiry
SCTB-H127 Recombinant Human Anti-CD40 x Human Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD28 CD40 Inquiry
SCDB-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 CD40 Inquiry
FABIG-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 CD40 Inquiry
TRIB-H232 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD40 Inquiry
BSIG-H230 Human Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD40 Inquiry
CROSSAB-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD40 Inquiry
IGFV-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD40 Inquiry
BSDB-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (Diabody) Human Diabody CD28 CD40 Inquiry
BSFAB-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD40 Inquiry
BSFV-H230 Recombinant Human Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD40 Inquiry
SCTB-028 Recombinant Anti-CD40 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD28 CD40 Inquiry
SCDB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 CD40 Inquiry
FABIG-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 CD40 Inquiry
TRIB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD40 Inquiry
BSIG-056 Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD40 Inquiry
CROSSAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD40 Inquiry
IGFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD40 Inquiry
BSDB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Diabody) Human Diabody CD28 CD40 Inquiry
BSFAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD40 Inquiry
BSFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD40 Inquiry
FABIG-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 EPCAM Inquiry
FABIG-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 EGFR Inquiry
FABIG-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 CD44 Inquiry
FABIG-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 CD30 Inquiry
FABIG-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 CD3 Inquiry
FABIG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD28 Inquiry
FABIG-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 CD28 Inquiry
FABIG-002 Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Fab-IgG) Human Fab-IgG Ad Fiber Knob CD40 Inquiry
TRIB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Triple Body) Human Triple Body CD28 CSPG4 Inquiry
TRIB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Triple Body) Human Triple Body CD28 MUC1 Inquiry
TRIB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Triple Body) Human Triple Body CD28 HN Inquiry
TRIB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Triple Body) Human Triple Body CD28 FOLR1 Inquiry
TRIB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Triple Body) Human Triple Body CD28 EPCAM Inquiry
TRIB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Triple Body) Human Triple Body CD28 EGFR Inquiry
TRIB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD44 Inquiry
TRIB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD30 Inquiry
TRIB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD3 Inquiry
TRIB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD28 Inquiry
TRIB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Triple Body) Human Triple Body CD19 CD28 Inquiry
TRIB-002 Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Triple Body) Human Triple Body Ad Fiber Knob CD40 Inquiry
BSIG-063 Anti-CD28 x Anti-CSPG4 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CSPG4 Inquiry
BSIG-062 Anti-CD28 x Anti-MUC1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 MUC1 Inquiry
BSIG-061 Anti-CD28 x Anti-HN Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 HN Inquiry
BSIG-060 Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 FOLR1 Inquiry
BSIG-059 Anti-CD28 x Anti-EPCAM Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 EPCAM Inquiry
BSIG-058 Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 EGFR Inquiry
BSIG-057 Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD44 Inquiry
BSIG-055 Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD30 Inquiry
BSIG-054 Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD3 Inquiry
BSIG-050 Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD28 Inquiry
BSIG-040 Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 CD28 Inquiry
BSIG-002 Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (IgG-IgG) Human IgG-IgG Ad Fiber Knob CD40 Inquiry
CROSSAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (CrossMab) Human CrossMab CD28 CSPG4 Inquiry
CROSSAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (CrossMab) Human CrossMab CD28 MUC1 Inquiry
CROSSAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (CrossMab) Human CrossMab CD28 HN Inquiry
CROSSAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (CrossMab) Human CrossMab CD28 FOLR1 Inquiry
CROSSAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (CrossMab) Human CrossMab CD28 EPCAM Inquiry
CROSSAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD28 EGFR Inquiry
CROSSAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD44 Inquiry
CROSSAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD30 Inquiry
CROSSAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD3 Inquiry
CROSSAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD28 Inquiry
CROSSAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD19 CD28 Inquiry
CROSSAB-002 Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (CrossMab) Human CrossMab Ad Fiber Knob CD40 Inquiry
IGFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CSPG4 Inquiry
IGFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 MUC1 Inquiry
IGFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 HN Inquiry
IGFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 FOLR1 Inquiry
IGFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 EPCAM Inquiry
IGFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 EGFR Inquiry
IGFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD44 Inquiry
IGFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD30 Inquiry
IGFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD3 Inquiry
IGFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD28 Inquiry
IGFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 CD28 Inquiry
IGFV-002 Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (IgG-scFv) Human IgG-scFv Ad Fiber Knob CD40 Inquiry
BSDB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Diabody) Human Diabody CD28 CSPG4 Inquiry
BSDB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Diabody) Human Diabody CD28 MUC1 Inquiry
BSDB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Diabody) Human Diabody CD28 HN Inquiry
BSDB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Diabody) Human Diabody CD28 FOLR1 Inquiry
BSDB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Diabody) Human Diabody CD28 EPCAM Inquiry
BSDB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD28 EGFR Inquiry
BSDB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD28 CD44 Inquiry
BSDB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD28 CD30 Inquiry
BSDB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD28 CD3 Inquiry
BSDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 CD28 Inquiry
BSDB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD19 CD28 Inquiry
BSDB-002 Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Diabody) Human Diabody Ad Fiber Knob CD40 Inquiry
BSFAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CSPG4 Inquiry
BSFAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 MUC1 Inquiry
BSFAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 HN Inquiry
BSFAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 FOLR1 Inquiry
BSFAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 EPCAM Inquiry
BSFAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 EGFR Inquiry
BSFAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD44 Inquiry
BSFAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD30 Inquiry
BSFAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD3 Inquiry
BSFAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD28 Inquiry
BSFAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 CD28 Inquiry
BSFAB-002 Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Tandem Fab) Human Tandem Fab Ad Fiber Knob CD40 Inquiry
BSFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CSPG4 Inquiry
BSFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 MUC1 Inquiry
BSFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 HN Inquiry
BSFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 FOLR1 Inquiry
BSFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 EPCAM Inquiry
BSFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 EGFR Inquiry
BSFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD44 Inquiry
BSFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD30 Inquiry
BSFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD3 Inquiry
BSFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD28 Inquiry
BSFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 CD28 Inquiry
BSFV-002 Recombinant Human Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Tandem scFv) Human Tandem scFv Ad Fiber Knob CD40 Inquiry

Background

CD40 is a type I membrane glycoprotein that is expressed on various antigen-presenting cells (APCs), such as B cells, macrophages, and dendritic cells. The binding of CD40 and CD28 to their respective ligands provides co-stimulatory signals that activate T cells. Anti-CD28 and CD40 bispecific antibodies (BsAbs) recognize T cells with one arm, and APCs with the other. This strategy mitigates the T cell receptor (TCR) dependent activation threshold for T cells, resulting in enhanced proliferation, cytokine production, and cell survivability. These BsAbs have potential in research on diseases, such as Rheumatoid arthritis and Type 1 diabetes (T1D).

Hierarchy of co-stimulatory interactions. (Edner, et al., 2020)

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