IVD Antibody Development Services for CEA Marker

Creative Biolabs is a world-leading service provider of application-specific antibody development. Here, we introduce our in vitro diagnostic (IVD) antibody development and immunoassay development services targeting the CEA marker. We are confident that our commitment to science and research will enable us to offer you the best products and services.

Carcinoembryonic Antigen (CEA)

Carcinoembryonic antigen (CEA) is a group of highly related glycoproteins involved in cell adhesion. CEA is usually produced in gastrointestinal tissues during fetal development but is stopped before birth. Therefore, CEA usually presents very low levels in the blood of healthy adults. However, serum levels are raised in certain types of cancer, which means that it can be used as a tumor marker in clinical trials.

Serum CEA levels in patients with colorectal cancer are generally higher than those in healthy people (approximately 2.5 μg/L or higher). The CEA measurement is mainly used as a tumor marker to monitor the treatment of colorectal cancer, to identify recurrence after surgical resection, to stage cancer or to localize cancer spread by measuring biological fluids. CEA levels may also be raised in gastric cancer, lung cancer, breast cancer, pancreatic cancer, and medullary thyroid cancer as well as some non-neoplastic diseases such as ulcerative colitis, pancreatitis, cirrhosis, COPD, Crohn's disease, hypothyroidism, and smokers.

Fig.1 CEA protein. (Ibrahim, et al., 2023)Fig.1 Schematic representation of the carcinoembryonic antigen (CEA) protein.1

CEA Marker of Endometriosis

CEA is a useful marker for the detection of recurrent disease in endometrial carcinoma patients. The value of CEA antigen is evaluated in combination with CA-125 and CA19-9 in patients with endometriosis and is found distinguish between endometriosis and malignant tumors.

IVD Antibody Development Service Targeting CEA Marker

IVD antibodies are extensively used in immunodiagnostic tools for disease screening and therapeutic monitoring. Through our role as a leading antibody service provider, Creative Biolabs is well-positioned to develop high-quality anti-CEA antibodies. Besides antibody generation, Creative Biolabs also offers diagnostic immunoassay development services, including feasibility analysis, assay design, assay protocol establishment, assay optimization, and kit production.

Creative Biolabs has successfully completed numerous IVD antibody generation and development projects for clients across the globe. If you are interested in our IVD antibody discovery services, please contact us for more details.

Reference

  1. Ibrahim, May R., and Yaser E. Greish. "MOF-based biosensors for the detection of carcinoembryonic antigen: A concise review." Molecules 28.16 (2023): 5970.

For Research Use Only.



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