Human GM-CSF antibody pair set for ELISA useCapture Antibody: Mouse Monoclonal IgG1Detection Antibody: Rat Monoclonal IgG2a
Specific Inquiry(Note: Please select the requirements to fit you project. If you have any other requirements, please specify. If no specific requirements, you don't need to select any button.)
Antigen Detail | |
|---|---|
| Target | GM-CSF |
| Description | Granulocyte macrophage colony stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomer secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts Glycoprotein cytokine. The naturally occurring drug analogs of GM-CSF are called molgramostim. Unlike granulocyte colony stimulating factor, which promotes the proliferation and maturation of neutrophils, GM-CSF affects more cell types, especially macrophages and eosinophils. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Mouse |
| Production | Cell culture |
| Clone | IV01391 |
| Isotype | IgG1 |
| Purification | DEAE ion-exchange chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Rat |
| Production | Cell culture |
| Conjugation | Biotin |
| Clone | RD1025 |
| Isotype | IgG2a |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, containing 1% BSA and 125 mM trehalose |
General Product Property | |
|---|---|
| Product Overview | Human GM-CSF antibody pair set for ELISA use Capture Antibody: Mouse Monoclonal IgG1 Detection Antibody: Rat Monoclonal IgG2a |
| Specificity | Both the capture and the detection antibodies in this set react with natural and recombinant human GM-CSF. |
| Sensitivity | 2 pg/ml |
| Research Area | Inflammation; Immunology |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | CSF2 |
| Full Name | Granulocyte-macrophage colony-stimulating factor |
| Background | Granulocyte macrophage colony stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomer secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts Glycoprotein cytokine. Unlike granulocyte colony stimulating factor, which promotes the proliferation and maturation of neutrophils, GM-CSF affects more cell types, especially macrophages and eosinophils. |
| Alternative Names | CSF2, GMCSF, colony stimulating factor 2, CSF |
| Gene ID | 1437(Human); 12981(Mouse) |
| Uniprot ID | P04141(Human); P01587(Mouse) |
| GeneCards | CSF2 |
| HGNC | 2434 |
| Ensembl | ENSG00000164400 |
| OMIM | 138960 |
| Involvement in Disease | Diseases associated with CSF2 include Pulmonary Alveolar Proteinosis and Mucositis. |
| Function | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
| Related Pathways | Its related pathways are Transcriptional misregulation in cancer and RET signaling. |
For Research Use Only.
Related products
