MV-4-11 In Vitro ATP Assay (Cell Viability) (CAT#: ITS-1122-YF4314)

MV-4-11

Human

A model of human AML (acute myeloid leukemia) Acute myeloid leukemia (AML) is a malignant disorder of the progenitor cells in myeloid hematopoiesis and represents a genetically heterogeneous cancer.

MV(4;11)

Acute Myeloid Leukemia; AML

Oncology

In Vitro ATP Assay (Cell Viability)

MV-4-11-cell based In Vitro ATP Assay (Cell Viability)

Adenosine triphosphate (ATP) assay is another widely used cell viability assay. When the cancer cells undergo apoptosis or necrosis upon treatment with a compound, cellular ATP content decreases and it can be quantified by colorimetric, fluorometric or luminometric way. The latest bioluminescence assays measure cellular ATP content using the enzyme luciferase which is more sensitive and reproducible when determining cell viability compared to conventional assays.

Adenosine Triphosphate Assay

Cell Viability/Cytotoxicity and Antiproliferative Assays

Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.

Cell Viability Assay

Cell-based Viability Assays Based on Cellular Enzymes and Proteins