At Creative Biolabs, we offer comprehensive customized services for our Anti-ABO Monoclonal Antibody to support your therapeutic and drug development research. Our services include custom antibody production tailored to your specific requirements,
ensuring optimal performance and specificity. We provide antibody conjugation services for various applications, including flow cytometry, immunohistochemistry, and ELISA.
Additionally, our expert team offers glycan profiling, epitope mapping, and binding affinity analysis to enhance your research outcomes. With our state-of-the-art facilities and extensive experience in glycan-related research, Creative Biolabs ensures
high-quality, reproducible results to accelerate your scientific discoveries.
Please contact us directly and inquire about the specific anti-glycan antibody products you want or customize directly.
Q: How is the Anti-ABO Antibody produced and purified?
A: The Anti-ABO Antibody is typically produced through immunization of suitable animal hosts with ABO antigens or by recombinant techniques. Purification involves affinity chromatography or protein A/G purification methods to ensure high specificity and
purity.
Q: How does the Anti-ABO Antibody compare to other blood grouping antibodies in terms of specificity and sensitivity?
A: The Anti-ABO Antibody exhibits high specificity towards ABO antigens, crucial for accurate blood typing. Its sensitivity ensures reliable detection of ABO antibodies even in small quantities, making it indispensable in clinical diagnostics and research
applications.
Q: Can the Anti-ABO Antibody be used in non-human species or experimental models?
A: Yes, the Anti-ABO Antibody can be adapted for use in various non-human species and experimental models to simulate human blood group scenarios. This capability facilitates preclinical studies and expands its utility in biomedical research beyond human
applications.
Q: What advancements have been made in Anti-ABO Antibody engineering to improve its performance?
A: Recent advancements focus on engineering Anti-ABO Antibodies for enhanced affinity and reduced immunogenicity. Techniques such as glycoengineering and chimerization aim to optimize therapeutic potential while minimizing adverse effects, promoting safer
and more effective clinical applications.
Q: What are the potential applications of the Anti-ABO Antibody in research and clinical settings?
A: In research, the Anti-ABO Antibody is used to study blood group genetics, compatibility testing, and antigen-antibody interactions. Clinically, it plays a vital role in blood typing, antibody detection, and cross-matching for safe blood transfusions
and organ transplantation.
Full Name
ABO Antigen
Keywords
Blood Group B Transferase/GTB/ABO; ABO; GTB; A transferase; A3GALNT; A3GALT1; ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; ABO; B transferase; B(A) alpha-1,3-galactosyltransferase; EC 2.4.1.37; EC 2.4.1.40; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; GTB; Histo-blood group A transferase; histo-blood group A2 transferase; histo-blood group ABO system transferase; Histo-blood group B transferase; NAGAT
Background
This is an antigen of human blood. ABO antigens are carbohydrate molecules present on the surface of red blood cells and various tissues. They play a crucial role in blood transfusion compatibility, organ transplantation, and immune response. These antigens are classified into four blood groups: A, B, AB, and O, based on the presence or absence of specific glycan structures. Understanding ABO antigens is essential in therapeutic research for developing blood substitutes, improving transfusion safety, and designing targeted therapies for diseases involving glycan interactions. Researchers utilize anti-glycan antibodies to study these antigens, enabling advancements in immunology, hematology, and transfusion medicine.
