Blood Group Lewis X
Full Name
Blood Group Lewis X
Keywords
alpha-(1,3)-fucosyltransferase; CD15; EC 2.4.1; EC 2.4.1.-; EC 2.4.1.65; ELAM-1 ligand fucosyltransferase; ELFT; FCT3AELAM ligand fucosyltransferase; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); Fucosyltransferase 4; Fucosyltransferase IV; FUC-TIV; fucT-IV; FUTIV; Galactoside 3-L-fucosyltransferase; Lewis X; LeX; SSEA1; SSEA-1; stage-specific embryonic antigen 1; Galb1-4(Fuca1-3)GlcNAcb1--R
Background
It is a Lewis blood group related carbohydrate antigen, also known as X-hapten, Lewis X, 3-FAL, 3-fucosyl-N-acetyllactosamine, or CD15. The expression pattern of SSEA-1 antigen is different in humans than in mice. In mice, SSEA-1 is expressed on embryonic stem cells (ES), embryonal carcinoma cells (EC), 8-cell to blastocyst embryos, and a subset of embryonic inner cell mass. The expression on murine ES cells is decreased upon differentiation. In humans, however, SSEA-1 is not found on undifferentiated ES cells, but its expression is upregulated along with differentiation. CD15 is highly expressed on adult human granulocytes. It has been reported that SSEA-1 plays a role in cell adhesion and regulation of cell differentiation.
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Mouse Anti-Blood Group Lewis X Monoclonal Antibody, R-PE (AGM-075YJ)(CAT#: AGM-075YJ)Online InquiryHost: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: FC, IHC-Fr, IP
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: FC, IHC-Fr, IP
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: FC, IHC-P, FuncS
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: IHC, IHC-P, IHC-Fr, FC, ELISA
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: FC
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: WB, IP, IF, IHC-P, FC
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: Flow, ICC, IF
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: FC, IHC-P, IHC-Fr
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: ICC, IF, FC, IHC-P
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: Mouse, HumanApplication: FC, ICC, IF, IHC-Fr
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Host: MouseAntibody Isotype: IgG3Species Reactivity: HumanApplication: FC
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: Human, PigApplication: FC, IP
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: IF, IHC-P
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Host: MouseAntibody Isotype: IgMSpecies Reactivity: HumanApplication: ICC, IF, IHC-Fr, FC
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Host: MouseAntibody Isotype: IgG1Species Reactivity: HumanApplication: FC
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Host: MouseAntibody Isotype: IgG1Species Reactivity: HumanApplication: ELISA, WB, IHC, FC
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Host: HumanAntibody Isotype: IgG1Species Reactivity: HumanApplication: ELISA, WB, IHC, FC
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Host: MouseAntibody Isotype: IgM, κSpecies Reactivity: S. MinnesotaApplication: ELISA