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Klebsiella-focused Research-grade Drug Discovery Service

At the frontier of cutting-edge scientific advancements, Creative Biolabs is proud to be offering our comprehensive research-grade drug discovery service designed specifically for Klebsiella infection research. Our objective is to empower researchers by providing them with state-of-the-art research tools and technological know-how.

Klebsiella Infection Introduction

  • Klebsiella is a common gram-negative bacteria found in soil and water, among other environments. Moreover, it is present in the human intestines, but there are generally no health concerns there. On the other hand, this bacterium causes a variety of diseases, including meningitis, wound or infection at the surgical site, pneumonia, and bloodstream infections.
  • Klebsiella infections are more common in healthcare settings, especially among those who have weakened immune systems or have been hospitalized for a long time. This is because the bacterium can spread through direct contact between people or, less frequently, through environmental contamination. Ongoing research aims to better understand Klebsiella and how to manage drug-resistant strains.
  • The symptoms of a Klebsiella infection depend on the area of the body that's affected but can include fever, chills, flu-like symptoms, and in severe cases, shortness of breath and chest pain.
  • Pneumonia triggered by Klebsiella can result in lung abscess (a pus-filled cavity in the lung) and inflammation around the lungs. In bloodstream infections, the bacteria can quickly spread to other parts of the body.

Our Offerings

1. High-throughput screening.

Our high-throughput screening system employs sophisticated robotics, data processing, and control software to expeditiously perform millions of biochemical, genetic, or pharmacological assays. This allows scientists to identify active compounds, genes, or antibodies relevant to Klebsiella infection.

2. Medicinal chemistry.

Our medicinal chemistry service supports your drug discovery with lead optimization, SAR analysis, synthesis of drug precursors and more. Our team of experienced medicinal chemists provides innovative solutions for your unique research.

3. Pre-clinical testing.

We perform rigorous pre-clinical testing services to enable a smooth transition from research to clinical trials. This includes careful assessment of drug safety and dosage.

4. Pharmacokinetics & pharmacodynamics.

Investigate how potential anti-Klebsiella drugs interact within the body. Our service includes absorption, distribution, metabolism, and excretion (ADME) studies and drug-receptor interaction profiling.

5. Comprehensive analysis & reports.

We provide transparent, detailed, and easy-to-understand reports. Our experts will analyze the data and provide insights to help you make informed decisions on your drug development journey.

Fig. 1 Klebsiella quantitative proteomic analysis. (Hao, et al., 2022)Fig. 1 Workflow of the quantitative proteomic analysis of differentially expressed proteins in Klebsiella.1

The rise in multidrug-resistant Klebsiella infections poses significant global health challenges. At Creative Biolabs, our drug discovery service specializes in Klebsiella research, aiming to pave the way for the formulation of research-grade therapeutic drugs. Please contact us to advance your Klebsiella infection research together.

Reference:

  1. Hao, Ling, et al. "Molecular Characteristics and Quantitative Proteomic Analysis of Klebsiella pneumoniae Strains with Carbapenem and Colistin Resistance." Antibiotics 11.10 (2022): 1341.
For Research Use Only. We do not provide direct services or products for patients.
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For Research Use Only. We do not provide direct services or products for patients.

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