Creative Biolabs pioneer in providing top-notch, research-centered drug discovery services, specializing in the study of negative-sense single-stranded RNA ((-) ss-RNA) viruses. Our world-class facilities stand ready to facilitate the journey of scientists and researchers in uncovering and formulating therapeutic solutions targeted at these deleterious viruses.
Single-Stranded (-) RNA.
One of the distinguishing features of these viruses is the presence of a single-stranded, non-segmented, negative-sense RNA genome. Essentially, this means that the genome is oriented in reverse and requires translation into a positive-sense mRNA to be manipulated by the host cell.
Transcription.
The formation of mRNA in (-) ss-RNA viruses necessitates host cells' machinery. This is a multifaceted process that involves a variety of virus-encoded proteins.
Host range.
These viruses boast a wide host range, infecting entities ranging from plants and insects to humans, causing various diseases tailored to their specific hosts.
Bearing these attributes in mind, drug discovery and vaccine development initiatives count (-) ss-RNA viruses as a key focus. Our service aims to streamline these initiatives by offering a superior, research-driven platform for drug discovery.
Virus name | Disease |
---|---|
Influenza Virus (Myxovirus) | Influenza |
Measles virus | Measles |
Mumps virus | Mumps |
Respiratory syncytial virus | Respiratory infections |
Rabies Virus (Rhabdoviridae) | Rabies |
Ebola virus (Filoviridae) | Ebola virus disease |
Marburg Virus (Filoviridae) | Marburg virus disease |
Lassa Virus (Arenaviridae) | Lassa fever |
Nipah Virus (Paramyxoviridae) | Nipah virus infection |
Crimean-Congo Hemorrhagic Fever Virus (Bunyaviridae) | Crimean-Congo Hemorrhagic fever |
Hendra Virus (Paramyxoviridae) | Hendra virus infection |
Tab.1 Examples of (-) ss-RNA viruses as well as their associated diseases.
Fig. 1 The virion structures peculiar to the (-) ss-RNA viruses.1
Our Services Include:
At Creative Biolabs, we orchestrate a dynamic platform that stimulates advanced research on (-) ss-RNA viruses. Our mission is to assist in the discovery of potential drugs that can combat and prevent diseases caused by these viruses. For further inquiries, please contact our team.
Reference: