Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (Diabody-CH3) (BSDBC-H237)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CD28 and anti-HN antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & HN

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising preventive/therapeutic agent

Related Disease

Tumors

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

Gene ID

912270

UniProt ID

Q9Q2W5

Alternative Names

Hemagglutinin-neuraminidase; HN

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-H237)

Specifications

Targets

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