Recombinant Human Anti-CD3 x Anti-VEGFR2 Bispecific Antibody (Single-chain Diabody) (SCDB-H283)

Recombinant Anti-CD3 x Anti-VEGFR2 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget T cells to tumor cells. It is designed for the research of Colorectal cancer (CRC); Non-small cell lung cancer (NSCLC); Glioblastoma therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & VEGFR2

Type

Single-chain Diabody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colorectal cancer (CRC); Non-small cell lung cancer (NSCLC); Glioblastoma

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

VEGFR2

Gene ID

3791

UniProt ID

A0A024RD88

Alternative Names

FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD3 x Anti-VEGFR2 Bispecific Antibody (Single-chain Diabody) (CAT#: SCDB-H283)

Specifications

Targets

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