Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) (BSTF-172)

Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-IL13 scFv is fused to the N-terminus of Fc via a hinge region while another anti-IL17 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Asthma therapy.

Datasheet INQUIRY

Specifications

Targets

IL13 & IL17

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Asthma

Targets

Target 1

IL13

Gene ID

3596

UniProt ID

P35225

Alternative Names

IL13; interleukin 13; P600; IL-13; interleukin-13

Target 2

IL17

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-172)

Specifications

Targets

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