Recombinant Human Anti-MUC1 x Human Anti-CD28 Bispecific Antibody (Single-chain Triplebody) (SCTB-H132)

Recombinant Anti-MUC1 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) is designed to be expressed as a single chain with three scFv units, two distal binding sites for MUC1 and a central site for CD28. It contains a His-tag at the C/N terminus for affinity purification. This BsAb can retarget T cells to tumor cells. It is designed for the research of Pancreatic cancer; Ovarian cancer; Breast cancer; Bile duct cancer (BDC) therapy.

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Specifications

Targets

CD28 & MUC1

Type

Single-chain Triplebody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Pancreatic cancer; Ovarian cancer; Breast cancer; Bile duct cancer (BDC)

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

MUC1

Gene ID

4582

UniProt ID

P15941

Alternative Names

MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-MUC1 x Human Anti-CD28 Bispecific Antibody (Single-chain Triplebody) (CAT#: SCTB-H132)

Specifications

Targets

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