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CD44 & CR3 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem Diabody) Human CD44 CR3 Inquiry
T-BSDB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem Diabody) Human CD44 CR3 Inquiry
SCIGG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scIgG) Human Single chain IgGs CD44 CR3 Inquiry
SCIGG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scIgG) Human Single chain IgGs CD44 CR3 Inquiry
FVTIG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD44 CR3 Inquiry
FVTIG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD44 CR3 Inquiry
BSSG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD44 CR3 Inquiry
BSSG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD44 CR3 Inquiry
IGLFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD44 CR3 Inquiry
IGLFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD44 CR3 Inquiry
BSGV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD44 CR3 Inquiry
BSGV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD44 CR3 Inquiry
BSDG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD44 CR3 Inquiry
BSDG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD44 CR3 Inquiry
BABFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD44 CR3 Inquiry
BABFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD44 CR3 Inquiry
FABVC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD44 CR3 Inquiry
FABVC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD44 CR3 Inquiry
SCDBC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
SCDBC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
BSDBC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
BSDBC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
SCDBF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
SCDBF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
BSFVF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
BSFVF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
BSDBF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
BSDBF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD44 CR3 Inquiry
BSTF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BSTF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BSCFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BSCFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
MNAB-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
MNAB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BSFC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BSFC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BSCC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BSCC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD44 CR3 Inquiry
BIBD-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Bibody) Human Bibody CD44 CR3 Inquiry
BIBD-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Bibody) Human Bibody CD44 CR3 Inquiry
FABFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD44 CR3 Inquiry
FABFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD44 CR3 Inquiry
MiniB-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Minibody) Human Minibody CD44 CR3 Inquiry
MiniB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Minibody) Human Minibody CD44 CR3 Inquiry
SCTB-H185 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD44 CR3 Inquiry
SCDB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD44 CR3 Inquiry
FABIG-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD44 CR3 Inquiry
TRIB-H295 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Triple Body) Human Triple Body CD44 CR3 Inquiry
BSIG-H293 Human Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD44 CR3 Inquiry
CROSSAB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (CrossMab) Human CrossMab CD44 CR3 Inquiry
IGFV-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD44 CR3 Inquiry
BSDB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody) Human Diabody CD44 CR3 Inquiry
BSFAB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD44 CR3 Inquiry
BSFV-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD44 CR3 Inquiry
SCTB-090 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD44 CR3 Inquiry
SCDB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD44 CR3 Inquiry
FABIG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD44 CR3 Inquiry
TRIB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Triple Body) Human Triple Body CD44 CR3 Inquiry
BSIG-121 Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD44 CR3 Inquiry
CROSSAB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (CrossMab) Human CrossMab CD44 CR3 Inquiry
IGFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD44 CR3 Inquiry
BSDB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody) Human Diabody CD44 CR3 Inquiry
BSFAB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD44 CR3 Inquiry
BSFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD44 CR3 Inquiry
BSFC-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD3 CD44 Inquiry
BSFC-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD28 CD44 Inquiry
BSFC-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-CH3) Mouse scFv-CH3 B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
BSCC-H244 Recombinant Human Anti-CD3 x Human Anti-CD44 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD3 CD44 Inquiry
BSCC-H233 Recombinant Human Anti-CD28 x Human Anti-CD44 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD28 CD44 Inquiry
BSCC-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD3 CD44 Inquiry
BSCC-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD28 CD44 Inquiry
BSCC-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-CH1/CL) Mouse scFv-CH1/CL B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
BIBD-H244 Recombinant Human Anti-CD3 x Human Anti-CD44 Bispecific Antibody (Bibody) Human Bibody CD3 CD44 Inquiry
BIBD-H233 Recombinant Human Anti-CD28 x Human Anti-CD44 Bispecific Antibody (Bibody) Human Bibody CD28 CD44 Inquiry
BIBD-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Bibody) Human Bibody CD3 CD44 Inquiry
BIBD-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Bibody) Human Bibody CD28 CD44 Inquiry
BIBD-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Bibody) Mouse Bibody B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
FABFV-H244 Recombinant Human Anti-CD3 x Human Anti-CD44 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 CD44 Inquiry
FABFV-H233 Recombinant Human Anti-CD28 x Human Anti-CD44 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 CD44 Inquiry
FABFV-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 CD44 Inquiry
FABFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 CD44 Inquiry
FABFV-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
MiniB-H244 Recombinant Human Anti-CD3 x Human Anti-CD44 Bispecific Antibody (Minibody) Human Minibody CD3 CD44 Inquiry
MiniB-H233 Recombinant Human Anti-CD28 x Human Anti-CD44 Bispecific Antibody (Minibody) Human Minibody CD28 CD44 Inquiry
MiniB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Minibody) Human Minibody CD3 CD44 Inquiry
MiniB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Minibody) Human Minibody CD28 CD44 Inquiry
MiniB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Minibody) Mouse Minibody B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
SCTB-H138 Recombinant Human Anti-CD44 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 CD44 Inquiry
SCTB-H128 Recombinant Human Anti-CD44 x Human Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD28 CD44 Inquiry
SCDB-H242 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 CD44 Inquiry
SCDB-H231 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 CD44 Inquiry
FABIG-H242 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 CD44 Inquiry
FABIG-H231 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 CD44 Inquiry
TRIB-H244 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (Triple Body) Human Triple Body CD3 CD44 Inquiry
TRIB-H233 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD44 Inquiry
BSIG-H242 Human Anti-CD3 x Anti-CD44 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 CD44 Inquiry
BSIG-H231 Human Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD44 Inquiry
CROSSAB-H242 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD3 CD44 Inquiry
CROSSAB-H231 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD44 Inquiry
IGFV-H242 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 CD44 Inquiry
IGFV-H231 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD44 Inquiry
BSDB-H242 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD3 CD44 Inquiry
BSDB-H231 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD28 CD44 Inquiry
BSFAB-H242 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 CD44 Inquiry
BSFAB-H231 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD44 Inquiry
BSFV-H242 Recombinant Human Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 CD44 Inquiry
BSFV-H231 Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD44 Inquiry
SCTB-040 Recombinant Anti-CD44 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 CD44 Inquiry
SCTB-029 Recombinant Anti-CD44 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD28 CD44 Inquiry
SCDB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 CD44 Inquiry
SCDB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 CD44 Inquiry
SCDB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Single-chain Diabody) Mouse Single-chain Diabody B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
FABIG-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 CD44 Inquiry
FABIG-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 CD44 Inquiry
FABIG-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-IgG) Mouse Fab-IgG B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
TRIB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Triple Body) Human Triple Body CD3 CD44 Inquiry
TRIB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD44 Inquiry
TRIB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Triple Body) Mouse Triple Body B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
BSIG-068 Anti-CD3 x Anti-CD44 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 CD44 Inquiry
BSIG-057 Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD44 Inquiry
BSIG-013 Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (IgG-IgG) Mouse IgG-IgG B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
CROSSAB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD3 CD44 Inquiry
CROSSAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD44 Inquiry
CROSSAB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (CrossMab) Mouse CrossMab B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
IGFV-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 CD44 Inquiry
IGFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD44 Inquiry
IGFV-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (IgG-scFv) Mouse IgG-scFv B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
BSDB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD3 CD44 Inquiry
BSDB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD28 CD44 Inquiry
BSDB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Diabody) Mouse Diabody B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
BSFAB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 CD44 Inquiry
BSFAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD44 Inquiry
BSFAB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma 38C13 Idiotype CD44 Inquiry
BSFV-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 CD44 Inquiry
BSFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD44 Inquiry
BSFV-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma 38C13 Idiotype CD44 Inquiry

Background

CD44, a cell surface glycoprotein widely expressed by various cell types including immune cells, plays a crucial role in processes such as lymphocyte activation, homing, and extravasation. CD44 is also implicated in cancer metastasis and tumor microenvironment modulation. CR3 (complement receptor 3), also known as macrophage-1 antigen or CD11b/CD18, is a member of the β2 integrin family expressed on the surface of leukocytes. It functions as a receptor for various ligands and is involved in phagocytosis, cell-mediated cytotoxicity, and the regulation of immune responses. The anti-CD44×anti-CR3 bispecific antibody (BsAb) can be constructed to simultaneously bind to CD44-expressing cells and CR3-expressing immune cells, modulating cellular interactions, immune responses, and potentially enhancing macrophages-mediated cytotoxicity against CD44-expressing target cells. This BsAb can be used in the research of glioblastoma and squamous cancer therapy.

Fig.1 Functional mechanisms of CD44 and CR3. (Senbanjo and Meenakshi, 2017; Lőrincz, et al., 2019) Fig.1 Functions of CD44 and CR3.1,2

References

  1. Senbanjo, Linda T., and Meenakshi A. Chellaiah. "CD44: a multifunctional cell surface adhesion receptor is a regulator of progression and metastasis of cancer cells." Frontiers in Cell and Developmental Biology 5 (2017): 18.
  2. Lőrincz, Ákos M., et al. "Different calcium and Src family kinase signaling in Mac-1 dependent phagocytosis and extracellular vesicle generation." Frontiers in Immunology 10 (2019): 2942.
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