Short Decsription
This product is a 3-Hydroxyacyl ACP dehydrase-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL14-YTHDF2-ALKBH5-ALKBH5-DBCO) modification and Fatty acid synthesis-mediated (hnRNPs-Succinyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
ALKBH5
RNA types
mRNAs
Modification
ψ
Label
DBCO
RNA editing
G to A
Cell Type
M2 macrophages
Oligonucleotide
2'-H
RNA Construction
mRNAs-ψ-METTL14-YTHDF2-ALKBH5-ALKBH5-DBCO
Substrates
Succinyl-CoA
Cofactors
ADP
Pathway
Fatty acid synthesis
Epigenetic regulator
PKCλ/ι deficiency
Metabolic alteration
Favor the development of NEPC characteristics
Targeting diseases
Lung Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Fatty acid synthesis-hnRNPs-Succinyl-CoA-ADP

For Research Use Only | Not For Clinical Use

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