As a reliable and trusted contract research organization, Creative Biolabs has accumulated extensive
experience in the discovery and development of optimized therapeutic antibodies and proteins such as
monoclonal antibody, bispecific antibody, anti-idiotype antibody, antibody-drug conjugates, and enzymes,
cytokines, or membrane proteins etc. Relying on the expertise of senior scientists with more than 10 years
of experience and best-in-class equipment, our unique modules of integrated services enables us to guide our
clients through antibody or protein drug discovery challenge from target selection to IND regulatory
support.
Our Therapeutic Antibody and Protein Platform
Therapeutic antibodies are bio-pharmaceuticals used to treat various cancer, most therapeutic antibodies
are monoclonal antibodies. Therapeutic antibody binds to and recognizes the antigen receptor to activate or
inhibit wide range of biological processes for blocking cancer cell activity or triggering immune system to
fight cancer. Different from small molecule pharmaceutical, therapeutic antibody or protein are
characterized by high specificity, high affinity, and low immunogenicity. With years of expertise, we put
our solutions at your disposal to support your antibody/protein drug discovery and development process to
win the race in this field.
Fig.1 Simplified overview of monoclonal antibody (MAb) development strategies. (Mould, 2016)
End-to-end Platform From Gene to Bio-therapeutics
With extensive regulatory experience and rich laboratory capacity, Creative Biolabs offers our clients
with antibody and protein integrated platform covering antibody discovery, engineering, production,
structural and biochemical characterization, bioassays, in vivo animal testing, manufacture and
development, IND regulatory services. We're capable of gathering senior scientists across a wide range of
disciplines and backgrounds to support the accelerated & innovative services. We are committed to guaranteeing our clients can receive fully compliant data in the desired timeline. Our reliability
ensures our clients to return to us for their discovery and development needs. In addition, we provide
fully integrated bispecific antibody and antibody-drug conjugate modules for your choice.
To propose you the cutting-edge science, we are always continuously investing in new equipment to
provide our clients with access to the best technologies. We are dedicated to getting access to the most
complete solution to develop your drug candidate, as well as providing unparalleled therapeutic antibody
or protein candidates as a final goal.
Highlights
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Fully integrated end-to-end solutions,
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Client-focused and collaborative approaches,
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Senior scientists across a wide range of disciplines.
Creative Biolabs has successfully delivered many projects, as well as owns ample practical experience in
antibody and protein development. As a privileged partner, we are fully committed to contributing to the
success of your projects via client-focused, collaborative approach to creating reliable and trusted
partnerships. Our integrated end-to-end services will help you push the project forward to market
faster. Please contact us for detailed information and deeper communication to learn how we can be
involved in your projects.
References
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Mould, D.R, and Meibohm, B. Drug Development of Therapeutic Monoclonal Antibodies. BioDrugs. 2017, Aug;30(4):275-93.
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Tan, S., et al. An unexpected N-terminal loop in PD-1 dominates binding by nivolumab. Nat Commun. 2017, Feb 6;8:14369.