Short Decsription
This product is a Aldolase-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL14-YTHDF2-ALKBH5-HDACs-HEX) modification and Mevalonate pathway-mediated (nELAVL-Lactyl-CoA-ADP) metabolic analysis system.
RNA Construction
mRNAs-ψ-METTL14-YTHDF2-ALKBH5-HDACs-HEX
Pathway
Mevalonate pathway
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
nELAVL
Metabolic Reprogramming
Mevalonate pathway-nELAVL-Lactyl-CoA-ADP