Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CCL2 (clone 8PD3). We employs the pAS (pBAD-BFP-IL-4-KpnI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
human
Target
CCL2
Clone
8PD3
Species Reactivity
human
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
pBAD
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
pAS
Transformation Accuracy
0.88
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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