Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD2 ( clone 2B30J). We employs the AAV (EF1α-GFP-IL-10-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CD2
Clone
2B30J
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
EF1α
Effector Gene
IL-10
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.9
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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