Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD27 ( clone 4H922J). We employs the AAV (EF1α-GFP-c-Jun-KpnI) vector components and the SynExpress system of the exons Inversion/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CD27
Clone
4H922J
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
EF1α
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Inversion
Modification Domain
Exons
Carrier Type
AAV
Transformation Accuracy
0.87
Cell Culture
Adherent Culture

For Research Use Only | Not For Clinical Use

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