Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD276 ( clone 8H98R3). We employs the AAV (CMV-mScarlet-IL-17-PstI) vector components and the SynExpress system of the histone modification sites Knock-in/Delayed feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CD276
Clone
8H98R3
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mScarlet
Promoter
CMV
Effector Gene
IL-17
Insertion Sites
PstI
Gene Modification
Knock-in
Modification Domain
Histone modification sites
Carrier Type
AAV
Transformation Accuracy
0.92
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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