Description
This product utilizes dendritic cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD276 ( clone MA1B3-A1). We employs the AAV (CMV-mCherry-IL-10-HindIII) vector components and the SynExpress system of the single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Rabbit
Target
CD276
Clone
MA1B3-A1
Species Reactivity
Human
Cell Source
Dendritic cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
HindIII
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.92
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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