Description
This product utilizes NK cells that have been engineered with our proprietary GeneCircuit technology to specifically target CEACAM5 (clone CEAI). We employs the HBV (trc-RFP-β-catenin-NotI) vector components and the SynExpress system of the DNA methylation sites Knock-in/Adaptive feedback for a robust and sustained response against cancers.
Host
Humanized
Target
CEACAM5
Clone
CEAI
Species Reactivity
Human
Cell Source
NK cells
Sensor Gene
RFP
Promoter
trc
Effector Gene
β-catenin
Insertion Sites
NotI
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
HBV
Transformation Accuracy
0.88
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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