Description
This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target CEACAM5 (clone COL-1G2E). We employs the AAV (T7-mCherry-NF-κB-PstI) vector components and the SynExpress system of the lncRNA Base Editing/Delayed feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CEACAM5
Clone
COL-1G2E
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
T7
Effector Gene
NF-κB
Insertion Sites
PstI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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