Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CSF1R (clone RG7J1G5L5L). We employs the pUC (EF1α-mKate-c-Jun-KpnI) vector components and the SynExpress system of the DNA methylation sites Knock-in/Negative feedback for a robust and sustained response against cancers.
Host
Humanized
Target
CSF1R
Clone
RG7J1G5L5L
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
EF1α
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
pUC
Transformation Accuracy
0.86
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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