Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR6 (clone 4IB2E). We employs the AAV (CMV-mKate-c-Jun-KpnI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DR6
Clone
4IB2E
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
CMV
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.87
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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