Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target EpCAM ( clone 48.2D78). We employs the AAV (pBAD-Cy3-IL-4-XbaI) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
EpCAM
Clone
48.2D78
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
Cy3
Promoter
pBAD
Effector Gene
IL-4
Insertion Sites
XbaI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.86
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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