Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target FLT3 ( clone FLH902B3). We employs the AAV (SP6-mCherry-IL-10-HindIII) vector components and the SynExpress system of the single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
humanized
Target
FLT3
Clone
FLH902B3
Species Reactivity
human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
SP6
Effector Gene
IL-10
Insertion Sites
HindIII
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.99
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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