Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GD2 (clone hu3F8P). We employs the pCDNA (EF1α-Cy3-IL-10-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Humanized
Target
GD2
Clone
hu3F8P
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
Cy3
Promoter
EF1α
Effector Gene
IL-10
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
pCDNA
Transformation Accuracy
0.92
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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