Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GM2 (clone Hu3F8PV5L). We employs the pUC (EF1α-RFP-β-catenin-NotI) vector components and the SynExpress system of the DNA methylation sites Knock-in/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
GM2
Clone
Hu3F8PV5L
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
RFP
Promoter
EF1α
Effector Gene
β-catenin
Insertion Sites
NotI
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
pUC
Transformation Accuracy
0.95
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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