Description
This product utilizes regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPC3 ( clone 8-6B3Y). We employs the Lentivirus (EF1α-Cy2-TFIIB-XbaI) vector components and the SynExpress system of the single base pair Knockout/Balancing feedback for a robust and sustained response against cancers.
Host
Human
Target
GPC3
Clone
8-6B3Y
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
Cy2
Promoter
EF1α
Effector Gene
TFIIB
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.94
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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