Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPC3 ( clone M6B32D). We employs the Retrovirus (SV40-mKate-IL-10-EcoRI) vector components and the SynExpress system of the single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
GPC3
Clone
M6B32D
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
SV40
Effector Gene
IL-10
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Retrovirus
Transformation Accuracy
0.85
Cell Culture
Adherent Culture

For Research Use Only | Not For Clinical Use

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