Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPRC5D ( clone GB3444S). We employs the Lentivirus (CMV-mCherry-IL-4-KpnI) vector components and the SynExpress system of the miRNA Prime Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
GPRC5D
Clone
GB3444S
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Prime Editing
Modification Domain
miRNA
Carrier Type
Lentivirus
Transformation Accuracy
0.91
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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