Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target HMGB1 (clone 1G5L1G3). We employs the Lentivirus (CMV-BFP-IL-4-KpnI) vector components and the SynExpress system of the Coding regions Deletion/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
HMGB1
Clone
1G5L1G3
Species Reactivity
Human; Mouse; Rat; Pig; Cattle
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Deletion
Modification Domain
Coding regions
Carrier Type
Lentivirus
Transformation Accuracy
0.86
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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